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Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems
Cellular processes require specific interactions between cognate protein partners and concomitant discrimination against noncognate partners. Signal transduction by classical two-component regulatory systems typically entails an intermolecular phosphoryl transfer between a sensor kinase (SK) and a c...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545799/ https://ncbi.nlm.nih.gov/pubmed/23256153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212102110 |
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