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Intrinsic Negative Feedback Governs Activation Surge in Two-Component Regulatory Systems
PhoP and PhoQ comprise a two-component system in the bacterium Salmonella enterica. PhoQ is the sensor kinase/phosphatase that modifies the phosphorylation state of the regulator PhoP in response to stimuli. The amount of phosphorylated PhoP surges after activation, then declines to reach a steady-s...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713471/ https://ncbi.nlm.nih.gov/pubmed/22325356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.027 |
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