Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated in a phase 3 trial of treatment for AML. METHODS: We performed a mutational analy...

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Hauptverfasser: Patel, Jay P., Gönen, Mithat, Figueroa, Maria E., Fernandez, Hugo, Sun, Zhuoxin, Racevskis, Janis, Van Vlierberghe, Pieter, Dolgalev, Igor, Thomas, Sabrena, Aminova, Olga, Huberman, Kety, Cheng, Janice, Viale, Agnes, Socci, Nicholas D., Heguy, Adriana, Cherry, Athena, Vance, Gail, Higgins, Rodney R., Ketterling, Rhett P., Gallagher, Robert E., Litzow, Mark, van den Brink, Marcel R.M., Lazarus, Hillard M., Rowe, Jacob M., Luger, Selina, Ferrando, Adolfo, Paietta, Elisabeth, Tallman, Martin S., Melnick, Ari, Abdel-Wahab, Omar, Levine, Ross L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545649/
https://ncbi.nlm.nih.gov/pubmed/22417203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1112304
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