Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated in a phase 3 trial of treatment for AML. METHODS: We performed a mutational analy...

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Hlavní autoři: Patel, Jay P., Gönen, Mithat, Figueroa, Maria E., Fernandez, Hugo, Sun, Zhuoxin, Racevskis, Janis, Van Vlierberghe, Pieter, Dolgalev, Igor, Thomas, Sabrena, Aminova, Olga, Huberman, Kety, Cheng, Janice, Viale, Agnes, Socci, Nicholas D., Heguy, Adriana, Cherry, Athena, Vance, Gail, Higgins, Rodney R., Ketterling, Rhett P., Gallagher, Robert E., Litzow, Mark, van den Brink, Marcel R.M., Lazarus, Hillard M., Rowe, Jacob M., Luger, Selina, Ferrando, Adolfo, Paietta, Elisabeth, Tallman, Martin S., Melnick, Ari, Abdel-Wahab, Omar, Levine, Ross L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545649/
https://ncbi.nlm.nih.gov/pubmed/22417203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1112304
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