Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated in a phase 3 trial of treatment for AML. METHODS: We performed a mutational analy...

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主要な著者: Patel, Jay P., Gönen, Mithat, Figueroa, Maria E., Fernandez, Hugo, Sun, Zhuoxin, Racevskis, Janis, Van Vlierberghe, Pieter, Dolgalev, Igor, Thomas, Sabrena, Aminova, Olga, Huberman, Kety, Cheng, Janice, Viale, Agnes, Socci, Nicholas D., Heguy, Adriana, Cherry, Athena, Vance, Gail, Higgins, Rodney R., Ketterling, Rhett P., Gallagher, Robert E., Litzow, Mark, van den Brink, Marcel R.M., Lazarus, Hillard M., Rowe, Jacob M., Luger, Selina, Ferrando, Adolfo, Paietta, Elisabeth, Tallman, Martin S., Melnick, Ari, Abdel-Wahab, Omar, Levine, Ross L.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545649/
https://ncbi.nlm.nih.gov/pubmed/22417203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1112304
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