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Actinin-4 in keratinocytes regulates motility via an effect on lamellipodia stability and matrix adhesions

During wound repair, epidermal cells at the edge of an injury establish front-rear polarity through orchestrated changes in their cytoskeleton and adhesion structures. The polarity and directed migration of such cells is determined by the assembly, extension, and stabilization of a lamellipodium. Ac...

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Detalhes bibliográficos
Principais autores: Hamill, Kevin J., Hopkinson, Susan B., Skalli, Omar, Jones, Jonathan C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545541/
https://ncbi.nlm.nih.gov/pubmed/23085994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217406
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