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BPAG1e Maintains Keratinocyte Polarity through β4 Integrin–mediated Modulation of Rac 1 and Cofilin Activities

α6β4 integrin, a component of hemidesmosomes, also plays a role in keratinocyte migration via signaling through Rac1 to the actin-severing protein cofilin. Here, we tested the hypothesis that the β4 integrin-associated plakin protein, bullous pemphigoid antigen 1e (BPAG1e) functions as a scaffold fo...

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Detalhes bibliográficos
Main Authors: Hamill, Kevin J., Hopkinson, Susan B., DeBiase, Philip, Jones, Jonathan C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695802/
https://ncbi.nlm.nih.gov/pubmed/19403692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0051
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