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Loss of β-PIX inhibits focal adhesion disassembly and promotes keratinocyte motility via myosin light chain activation

During healing of the skin, the cytoskeleton of keratinocytes and their matrix adhesions, including focal adhesions (FAs), undergo reorganization. These changes are coordinated by small GTPases and their regulators, including the guanine nucleotide exchange factor β-PIX (also known as ARHGEF7). In f...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Hiroyasu, Sho, Stimac, Gregory P., Hopkinson, Susan B., Jones, Jonathan C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536915/
https://ncbi.nlm.nih.gov/pubmed/28596238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.196147
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