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Loss of β-PIX inhibits focal adhesion disassembly and promotes keratinocyte motility via myosin light chain activation

During healing of the skin, the cytoskeleton of keratinocytes and their matrix adhesions, including focal adhesions (FAs), undergo reorganization. These changes are coordinated by small GTPases and their regulators, including the guanine nucleotide exchange factor β-PIX (also known as ARHGEF7). In f...

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Publicat a:J Cell Sci
Autors principals: Hiroyasu, Sho, Stimac, Gregory P., Hopkinson, Susan B., Jones, Jonathan C. R.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536915/
https://ncbi.nlm.nih.gov/pubmed/28596238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.196147
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