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Triplex technology in studies of DNA damage, DNA repair, and mutagenesis
Triplex-forming oligonucleotides (TFOs) can bind to the major groove of homopurine-homopyrimidine stretches of double-stranded DNA in a sequence-specific manner through Hoogsteen hydrogen bonding to form DNA triplexes. TFOs by themselves or conjugated to reactive molecules can be used to direct sequ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545518/ https://ncbi.nlm.nih.gov/pubmed/21501652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2011.04.001 |
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