Llwytho...

Syntaxin-1 N-peptide and H(abc)-domain perform distinct essential functions in synaptic vesicle fusion

Among SNARE proteins mediating synaptic vesicle fusion, syntaxin-1 uniquely includes an N-terminal peptide (‘N-peptide’) that binds to Munc18-1, and a large, conserved H(abc)-domain that also binds to Munc18-1. Previous in vitro studies suggested that the syntaxin-1 N-peptide is functionally importa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Peng, Pang, Zhiping P, Yang, Xiaofei, Zhang, Yingsha, Rosenmund, Christian, Bacaj, Taulant, Südhof, Thomas C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: European Molecular Biology Organization 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545302/
https://ncbi.nlm.nih.gov/pubmed/23188083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.307
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