FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

microRNA abundance has been shown to depend on the amount of the microprocessor components or, in some cases, on specific auxiliary co-factors. In this paper, we show that the FUS/TLS (fused in sarcoma/translocated in liposarcoma) protein, associated with familial forms of Amyotrophic Lateral Sclero...

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Main Authors: Morlando, Mariangela, Dini Modigliani, Stefano, Torrelli, Giulia, Rosa, Alessandro, Di Carlo, Valerio, Caffarelli, Elisa, Bozzoni, Irene
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545295/
https://ncbi.nlm.nih.gov/pubmed/23232809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.319
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