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FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons
The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Here we report that FUS controls back-splicing reactions leading to circular RNA (circRNA) production. We identif...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379105/ https://ncbi.nlm.nih.gov/pubmed/28358055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14741 |
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