ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

Patient-derived induced pluripotent stem cells (iPSCs) provide an opportunity to study human diseases mainly in those cases for which no suitable model systems are available. Here, we have taken advantage of in vitro iPSCs derived from patients affected by amyotrophic lateral sclerosis (ALS) and car...

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發表在:Dis Model Mech
Main Authors: Lenzi, Jessica, De Santis, Riccardo, de Turris, Valeria, Morlando, Mariangela, Laneve, Pietro, Calvo, Andrea, Caliendo, Virginia, Chiò, Adriano, Rosa, Alessandro, Bozzoni, Irene
格式: Artigo
語言:Inglês
出版: The Company of Biologists 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486861/
https://ncbi.nlm.nih.gov/pubmed/26035390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020099
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