ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

Patient-derived induced pluripotent stem cells (iPSCs) provide an opportunity to study human diseases mainly in those cases for which no suitable model systems are available. Here, we have taken advantage of in vitro iPSCs derived from patients affected by amyotrophic lateral sclerosis (ALS) and car...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Lenzi, Jessica, De Santis, Riccardo, de Turris, Valeria, Morlando, Mariangela, Laneve, Pietro, Calvo, Andrea, Caliendo, Virginia, Chiò, Adriano, Rosa, Alessandro, Bozzoni, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
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Resource Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486861/
https://ncbi.nlm.nih.gov/pubmed/26035390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020099
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