ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

Patient-derived induced pluripotent stem cells (iPSCs) provide an opportunity to study human diseases mainly in those cases for which no suitable model systems are available. Here, we have taken advantage of in vitro iPSCs derived from patients affected by amyotrophic lateral sclerosis (ALS) and car...

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Bibliografski detalji
Izdano u:Dis Model Mech
Glavni autori: Lenzi, Jessica, De Santis, Riccardo, de Turris, Valeria, Morlando, Mariangela, Laneve, Pietro, Calvo, Andrea, Caliendo, Virginia, Chiò, Adriano, Rosa, Alessandro, Bozzoni, Irene
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Resource Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486861/
https://ncbi.nlm.nih.gov/pubmed/26035390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020099
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