ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

Patient-derived induced pluripotent stem cells (iPSCs) provide an opportunity to study human diseases mainly in those cases for which no suitable model systems are available. Here, we have taken advantage of in vitro iPSCs derived from patients affected by amyotrophic lateral sclerosis (ALS) and car...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Lenzi, Jessica, De Santis, Riccardo, de Turris, Valeria, Morlando, Mariangela, Laneve, Pietro, Calvo, Andrea, Caliendo, Virginia, Chiò, Adriano, Rosa, Alessandro, Bozzoni, Irene
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015
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Resource Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486861/
https://ncbi.nlm.nih.gov/pubmed/26035390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020099
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