Point Mutations in the ERα Gαi Binding Domain Segregate Nonnuclear from Nuclear Receptor Function

A subpopulation of plasma membrane-associated estrogen receptor (ER)α interact directly with G proteins and mediate nonnuclear receptor signaling. This mechanism underlies numerous processes, including important cardiovascular protective actions of estradiol (E(2)), such as the activation of endothe...

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Main Authors: Wu, Qian, Chambliss, Ken, Lee, Wan-Ru, Yuhanna, Ivan S., Mineo, Chieko, Shaul, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545213/
https://ncbi.nlm.nih.gov/pubmed/23242705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1378
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