Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

Steroid hormone receptors function classically in the nucleus as transcription factors. However, recent data indicate that there are also non-nuclear subpopulations of steroid hormone receptors, including estrogen receptors (ERs), that mediate membrane-initiated signaling of unclear basis and signif...

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Hauptverfasser: Chambliss, Ken L., Wu, Qian, Oltmann, Sarah, Konaniah, Eddy S., Umetani, Michihisa, Korach, Kenneth S., Thomas, Gail D., Mineo, Chieko, Yuhanna, Ivan S., Kim, Sung Hoon, Madak-Erdogan, Zeynep, Maggi, Adriana, Dineen, Sean P., Roland, Christina L., Hui, David Y., Brekken, Rolf A., Katzenellenbogen, John A., Katzenellenbogen, Benita S., Shaul, Philip W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898582/
https://ncbi.nlm.nih.gov/pubmed/20577047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38291
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