Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

Steroid hormone receptors function classically in the nucleus as transcription factors. However, recent data indicate that there are also non-nuclear subpopulations of steroid hormone receptors, including estrogen receptors (ERs), that mediate membrane-initiated signaling of unclear basis and signif...

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Hlavní autoři: Chambliss, Ken L., Wu, Qian, Oltmann, Sarah, Konaniah, Eddy S., Umetani, Michihisa, Korach, Kenneth S., Thomas, Gail D., Mineo, Chieko, Yuhanna, Ivan S., Kim, Sung Hoon, Madak-Erdogan, Zeynep, Maggi, Adriana, Dineen, Sean P., Roland, Christina L., Hui, David Y., Brekken, Rolf A., Katzenellenbogen, John A., Katzenellenbogen, Benita S., Shaul, Philip W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898582/
https://ncbi.nlm.nih.gov/pubmed/20577047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38291
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