Sickle Cell Trait and the Risk of Plasmodium falciparum Malaria and Other Childhood Diseases

BACKGROUND: The gene for sickle hemoglobin (HbS) is a prime example of natural selection. It is generally believed that its current prevalence in many tropical populations reflects selection for the carrier form (sickle cell trait [HbAS]) through a survival advantage against death from malaria. Neve...

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Hauptverfasser: Williams, Thomas N., Mwangi, Tabitha W., Wambua, Sammy, Alexander, Neal D., Kortok, Moses, Snow, Robert W., Marsh, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545189/
https://ncbi.nlm.nih.gov/pubmed/15942909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/430744
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