An Immune Basis for Malaria Protection by the Sickle Cell Trait

BACKGROUND: Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate. While it probably involves innate factors such as the reduc...

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Detalhes bibliográficos
Main Authors: Williams, Thomas N, Mwangi, Tabitha W, Roberts, David J, Alexander, Neal D, Weatherall, David J, Wambua, Sammy, Kortok, Moses, Snow, Robert W, Marsh, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140945/
https://ncbi.nlm.nih.gov/pubmed/15916466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020128
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