Unprecedented Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2

Modifications and loss of bases are frequent types of DNA lesions, often handled by the base excision repair (BER) pathway. BER is initiated by DNA glycosylases, generating abasic (AP) sites that are subsequently cleaved by AP endonucleases, which further pass on nicked DNA to downstream DNA polymer...

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Hauptverfasser: Dalhus, Bjørn, Nilsen, Line, Korvald, Hanne, Huffman, Joy, Forstrøm, Rune Johansen, McMurray, Cynthia T, Alseth, Ingrun, Tainer, John A, Bjørås, Magnar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545110/
https://ncbi.nlm.nih.gov/pubmed/23245849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.11.004
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