Unprecedented Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2

Modifications and loss of bases are frequent types of DNA lesions, often handled by the base excision repair (BER) pathway. BER is initiated by DNA glycosylases, generating abasic (AP) sites that are subsequently cleaved by AP endonucleases, which further pass on nicked DNA to downstream DNA polymer...

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Detalhes bibliográficos
Main Authors: Dalhus, Bjørn, Nilsen, Line, Korvald, Hanne, Huffman, Joy, Forstrøm, Rune Johansen, McMurray, Cynthia T, Alseth, Ingrun, Tainer, John A, Bjørås, Magnar
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545110/
https://ncbi.nlm.nih.gov/pubmed/23245849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.11.004
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