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P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

In mammalian cells, proteins involved in mRNA silencing and degradation localize to discrete cytoplasmic foci called processing or P-bodies. Here we show that microscopically visible P-bodies are greatly diminished following West Nile viral infection, but the component proteins are not depleted. On...

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Detaylı Bibliyografya
Asıl Yazarlar: Chahar, Harendra S., Chen, Shuiping, Manjunath, N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545066/
https://ncbi.nlm.nih.gov/pubmed/23102969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.09.041
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