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Mutants of Human αB-Crystallin Cause Enhanced Protein Aggregation and Apoptosis in Mammalian Cells: Influence of co-expression of HspB1
Mutations of human αB-crystallin cause congenital cataract and cardio-myopathy by protein aggregation and cell death. How mutations of αB-crystallin become pathogenic is poorly understood. To better understand the cellular events related to protein aggregation and cell death, we transfected cataract...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544980/ https://ncbi.nlm.nih.gov/pubmed/23194663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.051 |
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