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Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners

HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mutations in HSPB5 have been found to cause cataract, but are also associated with a subgroup of myofibrillar myopathies. Cells expressing each of these HSPB5 mutants are characterized by the appearance of protei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hussein, Rasha M., Benjamin, Ivor J., Kampinga, Harm H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427338/
https://ncbi.nlm.nih.gov/pubmed/25961584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126761
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