Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model

Atherosclerosis is a complex disease resulting from the interaction of multiple genes. We have used the Ldlr knockout mouse model in an interspecific genetic cross to map atherosclerosis susceptibility loci. A total of 174 (MOLF/Ei × B6.129S7-Ldlr(tm1Her)) × C57BL/6J-Ldlr(tm1Her) backcross mice, hom...

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Detalhes bibliográficos
Main Authors: Welch, Carrie L., Bretschger, Sara, Latib, Nashat, Bezouevski, Mikhail, Guo, Yan, Pleskac, Nick, Liang, Chien-Ping, Barlow, Courtenay, Dansky, Hayes, Breslow, Jan L., Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35448/
https://ncbi.nlm.nih.gov/pubmed/11438740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141239098
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