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PAR1b takes the stage in the morphogenetic and motogenetic activity of Helicobacter pylori CagA oncoprotein

Helicobacter pylori CagA oncoprotein is critically involved in gastric carcinogenesis. Upon delivery into gastric epithelial cells via type IV secretion, CagA induces an extremely elongated cell-shape known as the hummingbird phenotype, which is associated with massive changes in actin cytoskeleton...

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Bibliographic Details
Main Authors: Yamahashi, Yukie, Hatakeyama, Masanori
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544774/
https://ncbi.nlm.nih.gov/pubmed/23076215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.21936
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