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PAR1b takes the stage in the morphogenetic and motogenetic activity of Helicobacter pylori CagA oncoprotein

Helicobacter pylori CagA oncoprotein is critically involved in gastric carcinogenesis. Upon delivery into gastric epithelial cells via type IV secretion, CagA induces an extremely elongated cell-shape known as the hummingbird phenotype, which is associated with massive changes in actin cytoskeleton...

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Autors principals: Yamahashi, Yukie, Hatakeyama, Masanori
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544774/
https://ncbi.nlm.nih.gov/pubmed/23076215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.21936
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