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A Reduction in Age-Enhanced Gluconeogenesis Extends Lifespan

The regulation of energy metabolism, such as calorie restriction (CR), is a major determinant of cellular longevity. Although augmented gluconeogenesis is known to occur in aged yeast cells, the role of enhanced gluconeogenesis in aged cells remains undefined. Here, we show that age-enhanced glucone...

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Autores principales: Hachinohe, Mayumi, Yamane, Midori, Akazawa, Daiki, Ohsawa, Kazuhiro, Ohno, Mayumi, Terashita, Yuzu, Masumoto, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544673/
https://ncbi.nlm.nih.gov/pubmed/23342062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054011
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