Reduction of Mitoferrin Results in Abnormal Development and Extended Lifespan in Caenorhabditis elegans

Iron is essential for organisms. It is mainly utilized in mitochondria for biosynthesis of iron-sulfur clusters, hemes and other cofactors. Mitoferrin 1 and mitoferrin 2, two homologues proteins belonging to the mitochondrial solute carrier family, are required for iron delivery into mitochondria. M...

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Autors principals: Ren, Yaguang, Yang, Su, Tan, Guoqiang, Ye, Wei, Liu, Danhui, Qian, Xu, Ding, Zhongying, Zhong, Yuhong, Zhang, Jingrui, Jiang, Dandan, Zhao, Yuhong, Lu, Jianxin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256167/
https://ncbi.nlm.nih.gov/pubmed/22253756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029666
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