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Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers
DNA methylation, consisting of the addition of a methyl group at the fifth-position of cytosine in a CpG dinucleotide, is one of the most well-studied epigenetic mechanisms in mammals with important functions in normal and disease biology. Disease-specific aberrant DNA methylation is a well-recogniz...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544446/ https://ncbi.nlm.nih.gov/pubmed/23342273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.22 |
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