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Novel Multiplex MethyLight Protocol for Detection of DNA Methylation in Patient Tissues and Bodily Fluids

Aberrant DNA methylation is a hallmark of cancer and is an important potential biomarker. Particularly, combined analysis of a panel of hypermethylated genes shows the most promising clinical performance. Herein, we developed, optimized and standardized a multiplex MethyLight assay to simultaneously...

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Bibliografske podrobnosti
Main Authors: Olkhov-Mitsel, Ekaterina, Zdravic, Darko, Kron, Ken, van der Kwast, Theodorus, Fleshner, Neil, Bapat, Bharati
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961737/
https://ncbi.nlm.nih.gov/pubmed/24651255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04432
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