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Energetics of Zinc-Mediated Interactions in the Allosteric Pathways of Metal Sensor Proteins
A metal-mediated interprotomer hydrogen bond has been implicated in the allosteric mechanism of DNA operator binding in several metal-sensing proteins. Using computational methods, we investigate the energetics of such zinc-mediated interactions in members of the ArsR/SmtB family of proteins (CzrA,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544337/ https://ncbi.nlm.nih.gov/pubmed/23214972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309170g |
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