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Simulations of Allosteric Motions in the Zinc Sensor CzrA
The zinc sensing transcriptional repressor Staphylococcus aureus CzrA represents an excellent model system to understand how metal sensor proteins maintain cellular metal homeostasis. Zn(II) binding induces a quaternary structural switch from a “closed” conformation to a more “open” conformation, re...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288340/ https://ncbi.nlm.nih.gov/pubmed/22007899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208047b |
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