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Differential roles of GluN2A- and GluN2B-containing NMDA receptors in neuronal survival and death

Glutamate-induced neurotoxicity is the primary molecular mechanism that induces neuronal death in a variety of pathologies in central nervous system (CNS). Toxicity signals are relayed from extracellular space to the cytoplasm by N-methyl-D-aspartate receptors (NMDARs) and regulate a variety of surv...

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Main Authors: Lujan, Brendan, Liu, Xiaoxuan, Wan, Qi
格式: Artigo
語言:Inglês
出版: e-Century Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544217/
https://ncbi.nlm.nih.gov/pubmed/23320134
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