Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pathway

AIM: To investigate the effect and mechanism of oridonin on the gastric cancer cell line HGC-27 in vitro. METHODS: The inhibitory effect of oridonin on HGC-27 cells was detected using the 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. After treatment with 10 μg/mL oridonin for...

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Detalhes bibliográficos
Main Authors: Sun, Ke-Wang, Ma, Ying-Yu, Guan, Tian-Pei, Xia, Ying-Jie, Shao, Chang-Ming, Chen, Le-Gao, Ren, Ya-Jun, Yao, Hai-Bo, Yang, Qiong, He, Xu-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544018/
https://ncbi.nlm.nih.gov/pubmed/23326121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i48.7166
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