d-Glucose modulates intestinal Niemann-Pick C1-like 1 (NPC1L1) gene expression via transcriptional regulation

The expression of intestinal Niemann-Pick C1-like 1 (NPC1L1) cholesterol transporter has been shown to be elevated in patients with diseases associated with hypercholesterolemia such as diabetes mellitus. High levels of glucose were shown to directly increase the expression of NPC1L1 in intestinal e...

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Main Authors: Malhotra, Pooja, Boddy, Craig S., Soni, Vinay, Saksena, Seema, Dudeja, Pradeep K., Gill, Ravinder K., Alrefai, Waddah A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543648/
https://ncbi.nlm.nih.gov/pubmed/23139223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00288.2012
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