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Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice

The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protein-coding genes, or inducible gene knockdown based on expression of short hairpin RNAs (shRNAs). The system is widely used in mice, however it requires robust expression of a tet transactivator protein...

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Autori principali: Takiguchi, Megumi, Dow, Lukas E., Prier, Julia E., Carmichael, Catherine L., Kile, Benjamin T., Turner, Stephen J., Lowe, Scott W., Huang, David C. S., Dickins, Ross A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543435/
https://ncbi.nlm.nih.gov/pubmed/23326559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054009
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