Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate

Sphingolipids play a role in the development of emphysema and ceramide levels are increased in experimental models of emphysema; however, the mechanisms of ceramide-related pulmonary emphysema are not fully understood. Here we examine mechanisms of ceramide-induced pulmonary emphysema. Male Sprague-...

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Bibliografiske detaljer
Main Authors: Yasuo, Masanori, Mizuno, Shiro, Allegood, Jeremy, Kraskauskas, Donatas, Bogaard, Harm J., Spiegel, Sarah, Voelkel, Norbert F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543313/
https://ncbi.nlm.nih.gov/pubmed/23326540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053927
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