Llwytho...

Targeting of TGFβ signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma

The miR-17∼92 cluster is thought to be an oncogene, yet its expression is low in glioblastoma multiforme (GBM) cell lines. This could allow unfettered expression of miR-17∼92 target genes such as connective tissue growth factor (CTGF; or CCN2), which is known to contribute to GBM pathogenesis. Indee...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fox, Jamie L., Dews, Michael, Minn, Andy J., Thomas-Tikhonenko, Andrei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543081/
https://ncbi.nlm.nih.gov/pubmed/23249750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036467.112
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