The C-terminal Peptide of Chondroadherin Modulates Cellular Activity by Selectively Binding to Heparan Sulfate Chains

Chondroadherin, a leucine-rich repeat family member, contains a very C-terminal sequence CKFPTKRSKKAGRH(359), now shown to bind to heparin with a K(D) of 13 μm. This observation led us to investigate whether chondroadherin interacts via this C-terminal heparin-binding domain with glycosaminoglycan c...

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Main Authors: Haglund, Lisbet, Tillgren, Viveka, Önnerfjord, Patrik, Heinegård, Dick
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543049/
https://ncbi.nlm.nih.gov/pubmed/23172228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430512
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