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Identification and Characterization of the Integrin α(2)β(1) Binding Motif in Chondroadherin Mediating Cell Attachment

Chondroadherin is a leucine-rich repeat protein known to mediate adhesion of isolated cells via the integrin α(2)β(1) and to interact with collagen. In this work, we show that cell adhesion to chondroadherin leads to activation of MAPKs but does not result in cell spreading and division. This is in...

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Autori principali: Haglund, Lisbet, Tillgren, Viveka, Addis, Laura, Wenglén, Christina, Recklies, Anneliese, Heinegård, Dick
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030393/
https://ncbi.nlm.nih.gov/pubmed/21127050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161141
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