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Chondroadherin Fragmentation Mediated by the Protease HTRA1 Distinguishes Human Intervertebral Disc Degeneration from Normal Aging

Chondroadherin, a member of the leucine-rich repeat family, has previously been demonstrated to be fragmented in some juveniles with idiopathic scoliosis. This observation led us to investigate adults with disc degeneration. Immunoblotting analysis demonstrated that non-degenerate discs from three d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Akhatib, Bashar, Önnerfjord, Patrik, Gawri, Rahul, Ouellet, Jean, Jarzem, Peter, Heinegård, Dick, Mort, John, Roughley, Peter, Haglund, Lisbet
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696698/
https://ncbi.nlm.nih.gov/pubmed/23673665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443010
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