ATP Hydrolysis Enhances RNA Recognition and Antiviral Signal Transduction by the Innate Immune Sensor, Laboratory of Genetics and Physiology 2 (LGP2)

Laboratory of genetics and physiology 2 (LGP2) is a member of the RIG-I-like receptor family of cytoplasmic pattern recognition receptors that detect molecular signatures of virus infection and initiate antiviral signal transduction cascades. The ATP hydrolysis activity of LGP2 is essential for anti...

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Bibliografiske detaljer
Main Authors: Bruns, Annie M., Pollpeter, Darja, Hadizadeh, Nastaran, Myong, Sua, Marko, John F., Horvath, Curt M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543043/
https://ncbi.nlm.nih.gov/pubmed/23184951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424416
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