A carregar...
The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly
Cytoplasmic pattern recognition receptors detect non-self RNAs during virus infections and initiate antiviral signaling. One receptor, MDA5, possesses essential signaling domains, but weak RNA binding. A second receptor, LGP2, rapidly detects diverse dsRNA species, but lacks signaling domains. Accum...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156907/ https://ncbi.nlm.nih.gov/pubmed/25127512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.07.003 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|