Structural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) Protein

UHRF1 is an important epigenetic regulator connecting DNA methylation and histone methylations. UHRF1 is required for maintenance of DNA methylation through recruiting DNMT1 to DNA replication forks. Recent studies have shown that the plant homeodomain (PHD) of UHRF1 recognizes the N terminus of unm...

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Detalhes bibliográficos
Main Authors: Cheng, Jingdong, Yang, Yi, Fang, Jian, Xiao, Jianxiong, Zhu, Tingting, Chen, Fei, Wang, Ping, Li, Ze, Yang, Huirong, Xu, Yanhui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543016/
https://ncbi.nlm.nih.gov/pubmed/23161542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415398
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