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Transport of the GlcNAc-1-phosphotransferase α/β-Subunit Precursor Protein to the Golgi Apparatus Requires a Combinatorial Sorting Motif

The Golgi-resident N-acetylglucosamine-1-phosphotransferase (PT) complex is composed of two α-, β-, and γ-subunits and represents the key enzyme for the biosynthesis of mannose 6-phosphate recognition marker on soluble lysosomal proteins. Mutations in the PT complex cause the lysosomal storage disea...

詳細記述

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書誌詳細
主要な著者: Franke, Mine, Braulke, Thomas, Storch, Stephan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543006/
https://ncbi.nlm.nih.gov/pubmed/23192343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407676
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