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PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage

p53 has a crucial role in governing cellular mechanisms in response to a broad range of genotoxic stresses. During DNA damage, p53 can either promote cell survival by activating senescence or cell-cycle arrest and DNA repair to maintain genomic integrity for cell survival or direct cells to undergo...

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Detalhes bibliográficos
Main Authors: Huang, B H, Zhuo, J L, Leung, C H W, Lu, G D, Liu, J J, Yap, C T, Hooi, S C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542616/
https://ncbi.nlm.nih.gov/pubmed/23235459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.180
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