Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens

Metastatic malignant melanoma is highly resistant to chemotherapy, and the average survival rate is under 1 year. The only FDA-approved conventional chemotherapy (i.e., dacarbazine) targets melanoma tumor cells by inducing a form of cell death referred to as apoptosis. However, dacarbazine exhibits...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Anvekar, R A, Asciolla, J J, Lopez-Rivera, E, Floros, K V, Izadmehr, S, Elkholi, R, Belbin, G, Sikora, A G, Chipuk, J E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542597/
https://ncbi.nlm.nih.gov/pubmed/23152056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.161
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars