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Clues to epidermal cancer proneness revealed by reconstruction of DNA repair-deficient xeroderma pigmentosum skin in vitro

Sun exposure has been clearly implicated in premature skin aging and neoplastic development. These features are exacerbated in patients with xeroderma pigmentosum (XP), a hereditary disease, the biochemical hallmark of which is a severe deficiency in the nucleotide excision repair of UV-induced DNA...

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Detalhes bibliográficos
Main Authors: Bernerd, Françoise, Asselineau, Daniel, Vioux, Corinne, Chevallier-Lagente, Odile, Bouadjar, Bakar, Sarasin, Alain, Magnaldo, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35425/
https://ncbi.nlm.nih.gov/pubmed/11438733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141221998
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