ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL

BACKGROUND: Acquired radioresistance of cancer cells remains a fundamental barrier to attaining the maximal efficacy of radiotherapy for the treatment of breast cancer. Anti-apoptotic proteins, such as Bcl-2 and Bcl-xL, play an important role in the radioresistance of cancer cells. In the present st...

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Hlavní autoři: Li, Ji-Yu, Li, Yu-Yang, Jin, Wei, Yang, Qing, Shao, Zhi-Ming, Tian, Xing-Song
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541995/
https://ncbi.nlm.nih.gov/pubmed/23259599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-102
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