Spatial Memory Deficits and Motor Coordination Facilitation in cGMP-Dependent Protein Kinase Type II-deficient Mice

Activity-dependent trafficking of AMPA receptors to synapses regulates synaptic strength. Activation of the NMDA receptor induces several second messenger pathways that contribute to receptor trafficking-dependent plasticity, including the NO pathway, which elevates cGMP. In turn, cGMP activates the...

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Autori principali: Wincott, Charlotte M., Kim, Seonil, Titcombe, Roseann F., Tukey, David S., Girma, Hiwot K., Pick, Joseph E., DeVito, Loren M., Hofmann, Franz, Hoeffer, Charles, Ziff, Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541678/
https://ncbi.nlm.nih.gov/pubmed/23103773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2012.10.003
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